BioLife Solutions, Inc.

BioLife Solutions, Inc. Class-defining solutions for bioproduction workflows.

BioLife Solutions is a leading supplier of class-defining cell and gene therapy bioproduction tools and services. Our tools portfolio includes our proprietary CryoStor® and HypoThermosol® biopreservation media for shipping and storage, the ThawSTAR® family of automated, water-free thawing products, evo® cold chain management system, Custom Biogenic Systems high capacity storage freezers, Stirling

Ultracold mechanical freezers, SciSafe biologic storage services, and Sexton Biotechnologies cell processing tools. For more information, please visit www.biolifesolutions.com, www.scisafe.com, www.stirlingultracold.com, or www.sextonbio.com and follow BioLife on Twitter.

It’s vital to properly cryopreserve and store CAR-T cells to ensure the cells can perform their duty of exterminating ca...
08/22/2024

It’s vital to properly cryopreserve and store CAR-T cells to ensure the cells can perform their duty of exterminating cancer tumors.

Your methods of cryopreservation, what cryogenic containers you store the CAR-T cells in, and how the cells are processed can impact cell viability, density, recovery and more.

In our latest white paper, Alex Sargent and the Cell & Gene Therapy team from Charles River Labs, along with Sean Werner (BioLife Solutions), summarize a study recently conducted that compares CAR-T cell storage across various primary containers, including our new CellSeal® CryoCase™, and the effects of different manufacturing methods on each container.

Read on to see the exciting results: https://ow.ly/ON7e50T2mFR

(This white paper was published in collaboration with Cell & Gene Therapy Insights and BioInsights.)

Today, Custom BioGenic Systems (CBS) launches a new, simplified website. You can easily navigate the new menu to see a s...
08/20/2024

Today, Custom BioGenic Systems (CBS) launches a new, simplified website.

You can easily navigate the new menu to see a sampling of cryogenic freezers, dewars, racks, accessories and monitoring systems.

If you’re ready to take your cryogenic sample organization, accessibility and safety to the next level, CBS is here to help.

Take a look at the new site and reach out with any questions: https://custombiogenics.com/

Don’t miss out!On Wednesday, August 21 at 11am EDT, Nature Research Custom Media and Charles River Labs (CLR) will host ...
08/15/2024

Don’t miss out!

On Wednesday, August 21 at 11am EDT, Nature Research Custom Media and Charles River Labs (CLR) will host a webcast that features Alex Sargent of CLR and Sean Werner of BioLife Solutions.

You will learn about:

• Performance expectations and risks of current primary storage containers for cell-based therapies

• Our NEW! CellSeal® CryoCase™ rigid storage container

• CAR-T cell study results comparing different cryopreservation containers

• Case study on closed-system cell therapy manufacturing processes

Register now: https://www.workcast.com/register?cpak=3627890718711728

SciSafe Inc, part of BioLife Solutions, launches a new, refreshed website today. Now you can quickly find biostorage ser...
08/13/2024

SciSafe Inc, part of BioLife Solutions, launches a new, refreshed website today.

Now you can quickly find biostorage service offerings directly at SciSafe.com. SciSafe can tailor a storage service plan to meet your needs, whether it’s hybrid-onsite, fully outsourced or customized.

The SciSafe team is ready to lessen your sample management “to-do list”.

� Explore the new site: https://www.scisafe.com/

Tomorrow (Saturday, August 10) is the Fred Hutch Obliteride 5K walk/run event in Seattle.BioLife Solutions is a sponsor,...
08/09/2024

Tomorrow (Saturday, August 10) is the Fred Hutch Obliteride 5K walk/run event in Seattle.

BioLife Solutions is a sponsor, and we have a team from our HQ participating in the event. The BioLife team has a goal of raising $3,000 for Obliteride. 100% of the proceeds directly support cancer research and treatments at Fred Hutch Cancer Center.

We hope to see you there!

Obliteride details: https://www.obliteride.org/

Donate to BioLife’s fundraiser: https://secure.fredhutch.org/site/TR/Obliteride/Obliteride?team_id=20785&pg=team&fr_id=2070

Fred Hutch Obliteride is a bike ride and 5K that empowers people to help cure cancer faster by raising funds for Fred Hutch Cancer Center. Every dollar we raise goes directly to work, advancing cancer prevention, detection, treatment, and cures that improve and save lives.

BioLife Solutions Reports Second Quarter 2024 Financial ResultsCell Processing revenue increased 11% sequentially to $18...
08/08/2024

BioLife Solutions Reports Second Quarter 2024 Financial Results

Cell Processing revenue increased 11% sequentially to $18.0 million

GAAP gross margin of 51% and non-GAAP adjusted gross margin of 52%

Conference call begins at 4:30 p.m. EDT, today, August 8, 2024

Cell Processing revenue increased 11% sequentially to $18.0 million GAAP gross margin of 51% and non-GAAP adjusted gross margin of 52% GAAP net loss from continuing operations of $7.1 million and...

Ultra-low temperature (ULT) or cryogenic freezer racks can help you improve sample accessibility, optimize cabinet space...
08/06/2024

Ultra-low temperature (ULT) or cryogenic freezer racks can help you improve sample accessibility, optimize cabinet space, and protect your samples from damage during handling.

Custom BioGenic Systems shares “Cold Storage Organization” tips on how to best utilize your freezer racks and keep freezer units operating at their peak.

Read on: https://custombiogenics.com/accessories/

Why is the thaw process so important when working with biologics and cell and gene therapies? Cell lines are fragile and...
08/01/2024

Why is the thaw process so important when working with biologics and cell and gene therapies?

Cell lines are fragile and need to be protected from the risks of osmotic shock and ice recrystallization during thawing. While there are multiple methods for sample thawing, using an automated system with precise warming profiles may help maximize cell recovery.

Our latest blog post reviews:

💧 Sample thawing significance in a biopreservation workflow

💧 Current thawing methods

💧 Benefits of using an automated thaw system

💧 Highlights of our new ThawSTAR® CSV System

Read on and let us know if you have any sample thawing questions.

https://go.biolifesolutions.com/l/103972/2024-08-01/5w3lqs

BioLife Solutions to Report Second Quarter 2024 Financial Results and Business Update on August 8, 2024
07/26/2024

BioLife Solutions to Report Second Quarter 2024 Financial Results and Business Update on August 8, 2024

BioLife Solutions, Inc. (NASDAQ: BLFS), a leading supplier of class-defining bioproduction tools and services for the cell and gene therapies ("CGT") and broader biopharma markets, today announced...

Do you wish your sample thawing technique was more precise? Do you worry your sample is not warming consistently? The Th...
07/25/2024

Do you wish your sample thawing technique was more precise? Do you worry your sample is not warming consistently?

The ThawSTAR® Automated Vial Thawing System replaces non-standardized methods of thawing samples with controlled, repeatable thawing programs specific to your vial. Worry less about sample contamination, as no water is used that could seep into vial caps, and focus more on the success of your research.

Our technicians can tailor the ThawSTAR algorithm to your specific application to help you optimize your thaw rate and improve the viability of your samples.

Ask us about our Vial Thawing options: https://go.biolifesolutions.com/l/103972/2024-05-20/5vqwjx

Custom BioGenic Systems (CBS) stainless steel ultra-low freezer racks can include a laser-cut number system or a custom ...
07/23/2024

Custom BioGenic Systems (CBS) stainless steel ultra-low freezer racks can include a laser-cut number system or a custom design on the drawers, so you can quickly inventory, organize and choose the right samples for your benchwork.

Our rack configurator experts can help you select the best racks, boxes and other accessories for your existing or new freezers.

Reach out to find out more about customization options: https://www.biolifesolutions.com/contact/sales-inquiries/

Don’t delay - the deadline to register for the Fred Hutch Obliteride 5K walk/run is July 25! Registration for the bike r...
07/18/2024

Don’t delay - the deadline to register for the Fred Hutch Obliteride 5K walk/run is July 25! Registration for the bike ride or virtual options are available until August 10.

BioLife is a proud sponsor, and we’d love to see you on August 10 at the University of Washington, Seattle.

The Fred Hutch Obliteride is a terrific way to raise money that supports cancer research. You can choose where your funds go and 100% of the funds go directly to the area you choose.

Check it out to learn more: https://www.obliteride.org/participate/walk-run.html

Join us for an upcoming webcast on August 21 to discuss the topic of “Comparing CAR-T cells across novel cryopreservatio...
07/16/2024

Join us for an upcoming webcast on August 21 to discuss the topic of “Comparing CAR-T cells across novel cryopreservation containers and platforms.”

We can’t wait to share the comparison study of CAR-T cells cryopreserved in our new rigid container, the CellSeal® CryoCase™, versus CAR-T cells cryopreserved in traditional cryobags and vials.

Featured speakers include Alex Sargent of Charles River Laboratories and Sean Werner of BioLife Solutions in collaboration with Nature Research Custom Media.

Register here to find out more: https://www.workcast.com/register?cpak=3627890718711728

Come find us at the 15th Annual ISHRS Hair Transplant 360 Workshop in St. Louis, MO on July 19-20. Sandy Jones and Shea ...
07/15/2024

Come find us at the 15th Annual ISHRS Hair Transplant 360 Workshop in St. Louis, MO on July 19-20. Sandy Jones and Shea Vincent will be onsite to discuss your hair graft storage and viability issues.

This workshop provides hair restoration physicians and assistants with hand-on coursework of Linear Strip Excision (LSE) and Follicular Unit Excision (FUE) procedures. There will also be insightful hair transplant lectures.

Check out the schedule and register here:https://web.cvent.com/event/3b42b679-0ba8-4d22-8cec-3e450ad5794d/summary

Would you like to receive a FREE printed poster on Biopreservation Best Practices for your laboratory?Read our new blog ...
07/11/2024

Would you like to receive a FREE printed poster on Biopreservation Best Practices for your laboratory?

Read our new blog post and fill out the form to have a poster shipped to your specified destination.

This blog post is a summary of the poster and highlights the importance of cryopreservation to maintain cell viability and functionality.

Biopreservation Best Practices we explore:

• Sample isolation and cell processing

• Formulation

• Aliquot and fill

• Controlled-rate freezing

• Storage and shipping

• Thawing

(Infographic created in collaboration with Cell & Gene Therapy Insights and BioInsights.)

Get your Biopreservation Best Practices poster print for your laboratory! Read our blog post and complete the form to receive your poster.

Particulates are an increasing challenge in cell and gene therapy manufacturing. Lowering particulate contamination may ...
07/09/2024

Particulates are an increasing challenge in cell and gene therapy manufacturing. Lowering particulate contamination may require new and innovative primary packaging containers and adjustments to current manufacturing processes.

Our latest white paper with Cell & Gene Therapy Insights highlights particulate issues with cryobags, fill & finish system controls, and provides the results of a study on our new rigid storage container, the CellSeal® CryoCase™.

Read on and send us any of your storage container questions.

https://go.biolifesolutions.com/l/103972/2024-06-05/5vt9rm

As we celebrate the birth of our nation on Thursday, we at BioLife Solutions are reminded of the pioneering spirit that ...
07/03/2024

As we celebrate the birth of our nation on Thursday, we at BioLife Solutions are reminded of the pioneering spirit that has driven progress and innovation throughout American history. Let's honor the courage and determination that make breakthroughs possible – from the laboratory to the clinic and beyond.

Wishing you a safe and joyous Independence Day filled with wonder, discovery and the spirit of innovation.

BioLife offices will be closed on Thursday, July 4 and Friday, July 5.

Contact us with any questions: https://www.biolifesolutions.com/contact/general-inquiries/

If you’re a hair restoration professional looking to better maintain the vitality of hair follicles during transplantati...
07/02/2024

If you’re a hair restoration professional looking to better maintain the vitality of hair follicles during transplantation, we can help.

HypoThermosol FRS is a specialized hypothermic (+2°C to +8°C) graft solution that tackles the challenges of hypothermia with balanced molecules and ions. This graft solution is backed by 20 years of scientific research and evidence.

Minimize environmental stressors and promote hair follicle growth by incorporating HypoThermosol FRS into your FUE transplant process.

Check out our “HypoThermosol for Hair” microsite to learn more.

https://go.biolifesolutions.com/hypothermosol-for-hair

If you’re using a manual water bath to thaw your cryovials with mixed results, then check out our line of ThawSTAR® Auto...
06/27/2024

If you’re using a manual water bath to thaw your cryovials with mixed results, then check out our line of ThawSTAR® Automated Vial Thawing Systems.

ThawSTAR water-free systems produce consistent thawing profiles each time, reducing variability from site-to-site and the risk of sample contamination.

Different models are available that are compatible with most major vial manufacturers. Our newest model, the ThawSTAR CSV, is designed specifically for Sexton Biotechnologies' CellSeal® Cryogenic Vials and CellSeal Connect Closed-System Vials.

Discover Vial Thawing Systems Home Precision cell vial thawing systems The ThawSTAR® Automated Thawing System replaces non-standardized manual methods of thawing samples with controlled thaw rates. ThawSTAR can be leveraged early in the R&D phase, scaled into commercial manufacturing and implemente...

Bloodworks Bio published a new poster at the 2024 ISCT, International Society for Cell & Gene Therapy Annual Meeting tha...
06/26/2024

Bloodworks Bio published a new poster at the 2024 ISCT, International Society for Cell & Gene Therapy Annual Meeting that features our biopreservation media, CryoStor®.

The study is a comparison of the clinical outcomes when using autologous HPCs (hematopoietic progenitor cells) cryopreserved in “home-brew” freeze media versus commercial freeze media (CryoStor CS10).

The results show slightly faster platelet recovery, fewer platelet transfusions and initial ANC recovery trended positively when using CryoStor CS10.

View the poster:https://www.biolifesolutions.com/wp-content/uploads/2024/06/Christian-Lin-Autologous-HPCs-cryopreserved-ISCT-2024-Poster-Final-6-5-24.pdf

Reach out to our Scientific Team if you have biopreservation best practice or freeze media questions:
https://evidence.biolifesolutions.com/ask-the-scientists

Custom BioGenic Systems (CBS) Isothermal freezers can safely preserve your samples from being contaminated by liquid nit...
06/25/2024

Custom BioGenic Systems (CBS) Isothermal freezers can safely preserve your samples from being contaminated by liquid nitrogen inside of the tank, even if samples are stored at the bottom.

How is this possible?

Check out this video highlighting the unique, jacketed dry-storage technology of these cryogenic freezers, plus many other benefits to make your lab or biobank easier and safer to operate.

This video showcases the features and benefits of the Isothermal family of cryogenic freezers BioLife Solutions has to offer.

06/21/2024

We are so grateful for our wonderful sponsors who help make Obliteride possible! Thank you BioLife Solutions, Inc., Audio Visual Factory Inc. - Event, Production, Design , Aegis Living, and Freestone Capital Management!

We are proud to sponsor the Fred Hutch Obliteride bike ride and 5K walk/run on Saturday, August 10 in Seattle, WA. This ...
06/21/2024

We are proud to sponsor the Fred Hutch Obliteride bike ride and 5K walk/run on Saturday, August 10 in Seattle, WA. This event raises funds for cancer research at the Fred Hutch Cancer Center.

Participants get to enjoy a “Friday Night Party” and a “Saturday Celebration” after the Obliteride. A team from our headquarters in Bothell is participating and we hope you will join us.

Learn more about Obliteride and how to support this great cause: https://www.obliteride.org/

CellSeal® Connect Vials help close gaps in your cell and gene therapy manufacturing with two weldable fill and retrieval...
06/19/2024

CellSeal® Connect Vials help close gaps in your cell and gene therapy manufacturing with two weldable fill and retrieval tubes that allow for closed-system, sterile processing of your intermediates.

This line extension of our CellSeal® platform gives you greater downstream flexibility. Connect Vials can be stored at -80°C/ultra-low, while our CellSeal Vials are ideal for -196°C/cryogenic temperatures. Both are compatible with semi-automated and automated fill & finish systems like the Sexton Biotechnologies Signata CT-5™ or CellSeal AF-500 system.

Curious? We’re here to discuss your processes and specific use case.

https://go.biolifesolutions.com/l/103972/2024-01-16/5vf1hj

Congratulations to Bristol Myers Squibb on the expanded FDA approval of their CAR-T cell therapy, Breyanzi®, to treat re...
06/10/2024

Congratulations to Bristol Myers Squibb on the expanded FDA approval of their CAR-T cell therapy, Breyanzi®, to treat relapsed or refractory Mantle Cell Lymphoma (MCL).

Breyanzi is the only FDA approved CAR-T cell therapy available for four specific subtypes of non-Hodgkin lymphoma. This expanded approval allows Breyanzi to treat the broadest types of B-cell malignancies.

Breyanzi utilizes our CryoStor® biopreservation media and Sexton Biotechnologies’ CellSeal® cryogenic storage vials. We are grateful to support cell and gene therapy researchers and manufacturers who develop these life-saving treatments to improve the lives of patients.

U.S. Food and Drug Administration Approves Bristol Myers Squibb’s Breyanzi as a New CAR T Cell Therapy for Relapsed or Refractory Mantle Cell Lymphoma

Particulate contamination in standard cryobags after filling and sealing was a hot topic of conversation at the 2024 ISC...
06/06/2024

Particulate contamination in standard cryobags after filling and sealing was a hot topic of conversation at the 2024 ISCT Annual Meeting.

Our latest white paper in collaboration with Cell & Gene Therapy Insights titled, “Can primary packaging selection help mitigate particulate risks in cell and gene therapy manufacturing?” addresses these concerns.

Sean Werner, Chief Technology Officer of Cell Processing, and other experts touch on:

• Cryobag particulate contamination challenges and prevention methods

• Particulate control during fill and finish

• Results from a case study on a new rigid, transparent container - the CellSeal® CryoCase™

Check it out: https://go.biolifesolutions.com/l/103972/2024-06-05/5vt9rm

Thank you to everyone who connected with us at the 2024 ISCT, International Society for Cell & Gene Therapy, Conference ...
06/05/2024

Thank you to everyone who connected with us at the 2024 ISCT, International Society for Cell & Gene Therapy, Conference last week.

Our top highlights include:

�Aby J. Mathew, PhD, and Co-Chair of the ISCT Translational Pathway Program, hosted the final “Launch & Patient Access Plenary” on Friday, which featured speakers from Allogene Therapeutics, AstraZeneca, Emily Whitehead Foundation and the U.S. Food and Drug Administration. The panel discussed advancing CGT operations, challenges, broadening patient access and more.

� The CellSeal® CryoCase™ Launch Event – it’s time to rethink therapy storage. CryoCase is the first rigid, fracture-resistant primary storage container.

� Reviewing your cryopreservation, cell processing/downstream processing, cold chain management, thawing and outsourced sample storage needs at the booth. Our team of scientists are available to answer questions about your specific cell type.

We want to hear from you: https://www.biolifesolutions.com/cell-processing/biopreservation/ask-the-scientists/

Do you need to increase your controlled freezing capabilities?The CBS IntelliRate™ i67C is a tabletop sized controlled r...
06/04/2024

Do you need to increase your controlled freezing capabilities?

The CBS IntelliRate™ i67C is a tabletop sized controlled rate freezer for when larger batch freezing throughput is needed, from mid-stage clinical research to commercial manufacturing volumes. It has a compact footprint, yet accommodates a larger sample capacity.

This model offers consistent and repeatable freeze runs of thousands of samples in one batch, which saves you time, space and operating costs.

Discover the IntelliRate i67C here: https://go.biolifesolutions.com/l/103972/2023-07-05/5v2rbf

Today we introduce the CellSeal® CryoCase™ closed-system container at the ISCT (International Society for Cell & Gene Th...
05/29/2024

Today we introduce the CellSeal® CryoCase™ closed-system container at the ISCT (International Society for Cell & Gene Therapy) Conference in Vancouver.

• The CellSeal CryoCase is the first rigid container designed for closed-system fill and retrieval for larger volumes of fluid (

New container developed for the needs of cell and gene therapy (CGT) primary packaging to replace cryopreservation bags with a fracture resistant, rigid construction built for both manual use and...

Join us at the ISCT (International Society for Cell & Gene Therapy) Annual Meeting on May 30 at 6:00pm, booth 109, for t...
05/28/2024

Join us at the ISCT (International Society for Cell & Gene Therapy) Annual Meeting on May 30 at 6:00pm, booth 109, for the launch of our NEW CellSeal® CryoCase™, a rigid primary storage container.

This event includes a welcome & introduction, a short CryoCase overview by Sean Werner and a champagne toast.

We can’t wait to celebrate this new container and advance the CGT industry with you!

Address

3303 Monte Villa Pkwy, Suite 310
Bothell, WA
98021

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm

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