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Metabolism.com Metabolism.com is managed by Gary Pepper, M.D., a retired endocrinologist with over 40 years of experience as clinician, educator and researcher
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Dr. Gary Pepper is the founder and editor-in-chief of Metabolism.com. Joining Dr. Pepper are several professional nutritionists, dieticians and specialists in oriental medicine. They are all here to provide you will answers to your questions as well as current, accurate information related to all things metabolism.

New research suggests the old diabetes medication, metformin, can have anti-aging properties. Dive into this short podca...
02/10/2024

New research suggests the old diabetes medication, metformin, can have anti-aging properties. Dive into this short podcast to learn about this most recent and unexpected development!

In this episode of *Dr. Pepper...Really?*, we explore the intriguing world of anti-aging research and the unexpected star—metformin.  A mainstay of treatment for Type 2 diabetes, metformin is now showing potential as a powerful tool in extend...

Losing weight is great. Losing muscle and skin tone is not great. In this short video we discuss nutrient dense meals, h...
30/09/2024

Losing weight is great. Losing muscle and skin tone is not great. In this short video we discuss nutrient dense meals, high in protein, fiber and micronutrients.

Dr. Pepper explains how to avoid malnutrition with high protein meals while rapidly losing weight on medications like , , TirzepatideThis vi...

We commonly think of melatonin as a chemical to help us sleep. But the gland in the brain known as the pineal gland is w...
23/09/2024

We commonly think of melatonin as a chemical to help us sleep. But the gland in the brain known as the pineal gland is where melatonin is made and is regulated by signals it gets from the eye. When the eye detects dimming of light it signals the pineal to make more melatonin. So it makes sense that the eye-melatonin relationship could play a role in the health of the eye. Here is some research that supports this concept

Use of the dietary supplement was seen to significantly reduce the risk for developing age-related macular degeneration and slow the progression of the condition, a new study found.

Along with rapid weight loss achieved with new GLP-1 medications comes the risk of malnutrition. Learn what can be done ...
05/09/2024

Along with rapid weight loss achieved with new GLP-1 medications comes the risk of malnutrition. Learn what can be done to prevent this unwanted accompaniment to otherwise successful dieting and what products may be coming to grocery store shelves soon, to assist with your goals!

Along with the amazing weight loss results with medications such as and , comes the unwanted complication of malnutrition. Join Dr. Gary Pepper in an insightful discussion of this "in the news" metabolic health ...

A recent study suggests that post menopausal women taking meds like Ozempic and Wegovy will lose more weight if they are...
06/08/2024

A recent study suggests that post menopausal women taking meds like Ozempic and Wegovy will lose more weight if they are also taking estrogen (HRT). Check out our latest video for more details:

New research appears to show that during menopause, women taking estrogen plus Ozempic lose more weight than with Ozempic only. What role does estrogen play ...

Listen to Dr. Gary Pepper's latest podcast, an interview with Kelly whose experience with menopausal weight gain led to ...
09/07/2024

Listen to Dr. Gary Pepper's latest podcast, an interview with Kelly whose experience with menopausal weight gain led to her choosing a GLP-1 agonist medication

Listen in on the  latest episode of Dr. Pepper...Really. This interview features Kelly's  personal account of using GLP-1 agonist medications to combat menopause-induced weight gain. Kelly's experience offers a glimpse into the potential...

Claims are being made for a wide range of health benefits attributed to use of GLP-1 agonist drugs like Ozempic, Mounjar...
03/07/2024

Claims are being made for a wide range of health benefits attributed to use of GLP-1 agonist drugs like Ozempic, Mounjaro, Wegovy etc. These benefits include reduced heart attack risk, improvement in fatty liver, arthritis, inflammatory diseases, kidney disease. Our latest blog puts these claims in perspective as weight loss itself can achieve these results without the drugs https://metabolism.com/the-glp-1-debate-separating-hype-from-health-benefits/

Here are the latest dietary recommendations for people on GLP-1 medications which include 60 to 75 gm of protein per day...
28/06/2024

Here are the latest dietary recommendations for people on GLP-1 medications which include 60 to 75 gm of protein per day but no more than 1.5 gm per kg of body weight (1kg = 2.2 lbs)

Researchers provide evidence-based suggestions for nutritional evaluation, treatment, and monitoring in patients taking anti-obesity medications (AOMs).

Criminals are becoming more adept at producing counterfeit weight loss medications. Here is our guide to help you naviga...
18/06/2024

Criminals are becoming more adept at producing counterfeit weight loss medications. Here is our guide to help you navigate these treacherous waters if you are in the market for a GLP-1 agent.

18/06/2024

Are the costs of GLP-1 drugs for weight loss overwhelming the healthcare system already? Or is it just about profits?

The risk is real, but understanding the true incidence of this severe complication of GLP-1 treatment is a complex probl...
11/06/2024

The risk is real, but understanding the true incidence of this severe complication of GLP-1 treatment is a complex problem.

Researchers reported a case of pancreatitis in two patients taking tirzepatide. The risk for pancreatitis is expected to rise with increased prescriptions of these agents.

Listen in to this fascinating podcast interview between Dr. Gary Pepper and Ellen regarding her experience with the new ...
04/06/2024

Listen in to this fascinating podcast interview between Dr. Gary Pepper and Ellen regarding her experience with the new miracle weight loss medication, semaglutide! Check out his other podcasts at Dr.Pepper....Really?

Join renowned endocrinologist Gary Pepper, M.D. as he delves into the real-world experiences of individuals using Ozempic and Rybelsus for weight loss. In this exclusive interview with Ellen, hear her account of her experience with these potent me...

The adrenal hormone cortisol is seriously misunderstood due to the potential for harm related to excessive levels that m...
29/05/2024

The adrenal hormone cortisol is seriously misunderstood due to the potential for harm related to excessive levels that may occur during stress. Learn more about the life saving as well as the potential harmful effects of adrenal hormones by listening to this short podcast at our channel Dr.Pepper...Really?

Embark on an enthralling exploration of the adrenal gland, both an unsung hero or potential enemy nestled atop our kidneys, with this comprehensive and fascinating overview. Dr. Gary Pepper, an esteemed endocrinologist with 40 years of experience,...

After 4 years of GLP1 treatment and many thousands of dollars later the average person is only down 10% of their origina...
25/05/2024

After 4 years of GLP1 treatment and many thousands of dollars later the average person is only down 10% of their original body weight. Is it really worth it?

These drugs are meant to be taken for life, but not everyone can afford to. May 22, 2024 When patients start on the latest obesity drugs, they find that their food cravings drop away, and then the pounds do too. But when patients go off the drugs, the gears shift into reverse: The food cravings cree...

Sleep apnea is much more common in those with central obesity (large belly) as the abdominal weight presses up against t...
22/04/2024

Sleep apnea is much more common in those with central obesity (large belly) as the abdominal weight presses up against the diaphragm (lungs) when lying in bed. I suspect that Ozempic (or any of these GLP-1 agents) does anything more for sleep apnea other than reduce the abdominal fat. That's great, don't get me wrong, but I fear the drug companies want to latch on to any added publicity they can get by making additional claims to "unexpected" benefits. Watch now as Lilly (maker of Ozempic) will also seek to get more "indications" from the FDA so they can market their product to doctors for sleep apnea etc.

I recently did an interview with Ellen who had unexpected and disturbing side effects with Ozempic. Not someone who is e...
17/04/2024

I recently did an interview with Ellen who had unexpected and disturbing side effects with Ozempic. Not someone who is easily discouraged Ellen is now on to another form of semaglutide treatment. Listen to her story on this podcast episode of Dr. Pepper...Really.

Join renowned endocrinologist Gary Pepper, M.D. as he delves into the real-world experiences of individuals using Ozempic and Rybelsus for weight loss. In this exclusive interview with Ellen, hear her account of her experience with these potent me...

I noticed an unusual number of new patients were people moving from out-of-state for a new job or relationship and would...
18/02/2024

I noticed an unusual number of new patients were people moving from out-of-state for a new job or relationship and would present to the office with a flare up of hyperthyroidism. A year later when their life returned to normal the thyroid function would return to normal also and treatment could be stopped. Seems to go along with these findings

Studies have shown that stress can cause thyroid disease. Why is this and what can be done to help patients?

New medications have revolutionized the Weight Loss industry. But rapid and dramatic weight loss can stir up your body a...
06/02/2024

New medications have revolutionized the Weight Loss industry. But rapid and dramatic weight loss can stir up your body and brain in ways you haven't even imagined. Check out our latest audio podcast on the subject. Comments are always welcome!

Join Dr. Gary Pepper, an esteemed endocrinologist with over four decades of expertise in patient care, research, and teaching, as he delves into the intricate relationship between weight loss, stress hormones, and their impact on our body in his l...

The FDA is investigating reports of hair loss associated with use of Ozempic. Read what an endocrinologist has to say ab...
16/01/2024

The FDA is investigating reports of hair loss associated with use of Ozempic. Read what an endocrinologist has to say about the possibilities and ways to avoid this perplexing problem.

Hair loss in those using semaglutide is being investigated . Could this be due to the effect on our hormones? Our hormone specialist explains the possibilities and what to do about it.

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