Neuromics

Neuromics We provide 2&3D Cell Based Assays, media and supplements (FBS) researching diseases and inventing new and better therapies. We stand behind our products.
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We are in the business of supporting those we keep us well and alive longer. We specialize in providing reagents and methods for the Neuroscience, Stem Cell and Regenerative Medicine Research Community. We serve scientists doing basic research and drug discovery in Neurodegenerative Diseases, Pain, Autoimmune Diseases and Cancer. Our unique value is based on providing reagents that are thoroughly

tested and characterized. If our reagents or cells do not meet expectations, we will fix it. We will either send equivalent replacement quantities or refund your money. Your satisfaction and feedback are important to our mutual success.

Our "in-vivo like" Blood-Brain Barrier (BBB) is being used to study the link between Periodontitis (PD) and Alzheimer's ...
09/16/2024

Our "in-vivo like" Blood-Brain Barrier (BBB) is being used to study the link between Periodontitis (PD) and Alzheimer's Disease (AD).

With the help of our model, the scientists found that not only do PD-induced exosomes cross the BBB, but they also compromise its integrity. TEER readings and expression of tight-junction proteins both decrease after exposure to the exosomes. These findings give some insight into how PD may contribute to the development of AD.

Image: TEER readings in Neuromics BBB model at different time points when blood side is exposed to PD exosomes (PD EXO) and health exosomes (Con EXO). Exposure to PD EXO decreases TEER readings.

Check our BBB Model-https://www.neuromics.com/3D45002. David Rupp Kathleen Stark Neuroscience News and Research Society for Neuroscience

Neuromics' Cancer-Associated Fibroblasts (CAFS) in ActionResearchers used our Human Kidney CAFS to show their impact on ...
09/11/2024

Neuromics' Cancer-Associated Fibroblasts (CAFS) in Action

Researchers used our Human Kidney CAFS to show their impact on Tumor Growth-https://www.neuromics.com/our-immortalized-cafs-in-action

Findings: When treated with the anti-CTLA-4 antibody (immunotherapy), the CAF-positive mice had a large tumor size. OM-RCA-01 was able to target both CAF-dependent and CAF-independent resistance to immunotherapy in the renal cancer in vivo model.

Check them out https://www.neuromics.com/fibroblasts-cafs-cancer-cells

Despite being on the market for less than a year, researchers just published a study citing our Immortalized Human Kidne...
09/11/2024

Despite being on the market for less than a year, researchers just published a study citing our Immortalized Human Kidney Cancer Associated Fibroblasts (CAFs) (cat. CAF110-IM) for the first time. The scientists investigated the therapeutic potential of the anti-fibroblast growth factor receptor 1 (FGFR1) monoclonal antibody OM-RCA-01, including in mice injected with our CAFs. Learn more in our blog post.

https://www.neuromics.com/our-immortalized-cafs-in-action

Through the end of September, Neuromics is offering 15% off ALL our human cells. We provide a diverse range of high-qual...
08/28/2024

Through the end of September, Neuromics is offering 15% off ALL our human cells. We provide a diverse range of high-quality and reliable human cells across various research areas. With customer citations to prove it, these cells play a critical role in advancing scientific understanding.

Learn more: https://www.neuromics.com/save-big-on-human-cells-this-september

It's time to plan for fall research projects! You'll need fetal bovine serum (FBS) if you have any cell culturing lined ...
08/22/2024

It's time to plan for fall research projects! You'll need fetal bovine serum (FBS) if you have any cell culturing lined up. Our FBS continues to demonstrate its reliability through customer citations. Two new studies are highlighted in our most recent blog post.

https://www.neuromics.com/rely-on-our-fbs-for-fall-research

I am proud to announce I have broken through and have 10,000 members in my LI Network (https://www.facebook.com/ #. I wo...
08/06/2024

I am proud to announce I have broken through and have 10,000 members in my LI Network (https://www.facebook.com/ #. I would like to thank my friends, colleagues, and clients. David Rupp Kathy Stark Neuromics
www.neuromics.com

Proven reagents for results you trust and understand

Last month, we highlighted the release of six human iPSC-derived brain cells and two immortalized cancer associated fibr...
08/01/2024

Last month, we highlighted the release of six human iPSC-derived brain cells and two immortalized cancer associated fibroblast (CAF) types in our blog. Believe it or not, the cell releases keep coming, as we've got six more iPSC-derived cell types to offer.

https://www.neuromics.com/even-more-ipsc-brain-cells

Glioblastomas are one of the most insidious forms of cancer. Today is   Neuromics
07/30/2024

Glioblastomas are one of the most insidious forms of cancer. Today is Neuromics

Neuromics is excited to announce the release of two more immortalized cancer-associated fibroblast (CAF) types. We are n...
07/25/2024

Neuromics is excited to announce the release of two more immortalized cancer-associated fibroblast (CAF) types. We are now offering immortalized versions of our human ovarian CAFs and lung squamous cell carcinoma CAFs. While normal CAFs can be passaged 3-5 times, immortalized CAFs can be passaged >10 times.

Learn more in our blog post: https://www.neuromics.com/more-immortalized-caf-types

Yes, there is a day for the brain. Neuromics is a proud provider of iPSC-derived and human primary cells, defined media,...
07/24/2024

Yes, there is a day for the brain. Neuromics is a proud provider of iPSC-derived and human primary cells, defined media, and supplements (https://www.neuromics.com/human-cells-tissue). Many Bio-pharmas are using these to discover new therapies. David Rupp Kathy Stark Society for Neuroscience Neuroscience News and Research

As IBA Lifesciences US distributor, Neuromics offers cutting-edge protein purification products. Strep-Tactin® 4Flow® Hi...
07/03/2024

As IBA Lifesciences US distributor, Neuromics offers cutting-edge protein purification products. Strep-Tactin® 4Flow® High Capacity is now available as a new and improved version of IBA's top-selling protein purification product.

Learn more: https://www.neuromics.com/iba-s-new-protein-purification-resin

Neuromics continues to grow our offerings of solutions designed for Neuroscientists. We are pleased to announce the addi...
06/24/2024

Neuromics continues to grow our offerings of solutions designed for Neuroscientists. We are pleased to announce the addition of motor, sensory, dopaminergic, glutaminergic, and GABAergic neurons (https://www.neuromics.com/neurons-astrocytes-schwann-cells-microglia).

We serve Neuroscientists in many Bio-Pharmas, Academic and National Labs. Society for Neuroscience Neuroscience News and Research Medical Alley The Michael J. Fox Foundation for Parkinson's Research Alzheimer's Association David Rupp Kathy Stark

After several months on backorder, our Exosome Free Fetal Bovine Serum (cat. FBS002-X) is back in stock. No matter your ...
06/18/2024

After several months on backorder, our Exosome Free Fetal Bovine Serum (cat. FBS002-X) is back in stock. No matter your cell culturing application, we've got you covered with our many FBS options. Check out all our products!

https://www.neuromics.com/fetal-bovine-serum-fbs-other-sera

Our Human Brain Astrocytes, Pericytes, and Microvascular Endothelial Cells were used in a newly released paper studying ...
05/09/2024

Our Human Brain Astrocytes, Pericytes, and Microvascular Endothelial Cells were used in a newly released paper studying the effects of hyperglycemia on the blood-brain barrier (BBB). The scientists built an in vitro BBB model by co-culturing the three cell types, finding disruptions to the integrity of the BBB after exposure to high glucose conditions.

Learn more in our new blog post:

https://www.neuromics.com/human-brain-cells-that-make-discoveries

Hypoglycemia and the breakdown of the Blood-Brain Barrier (BBB). This study shows how this breakdown contributes to stro...
05/09/2024

Hypoglycemia and the breakdown of the Blood-Brain Barrier (BBB). This study shows how this breakdown contributes to stroke (https://doi.org/10.1080/21688370.2024.2350821). It features the use of our Brain Microvascular Endothelial Cells and Astrocytes (https://www.neuromics.com/neurons-astrocytes-schwann-cells-microglia) to demonstrate this breakdown. David Rupp Neuromics Society for Neuroscience Neuroscience News and Research Medical Alley

Breakdown of blood-brain barrier (BBB) represents a key pathology in hyperglycemia-mediated cerebrovascular damage after an ischemic stroke. As changes in the level and nature of vasoactive agents ...

We are grateful to see our siRNA Transfection Kit (https://www.neuromics.com/transfection-kits) used in important resear...
04/29/2024

We are grateful to see our siRNA Transfection Kit (https://www.neuromics.com/transfection-kits) used in important research. Here, our kit is used to knock out a gene involved in alcohol-induced adolescent anxiety- EZH2-dependent epigenetic reprogramming in the central nucleus of amygdala regulates adult anxiety in both sexes after adolescent alcohol exposure (https://www.nature.com/articles/s41398-024-02906-y).
This research shows the impact of alcohol on mental health and potential treatments.

Neuromics raison d'etre is providing human cells and related 3-D models to drug hunters and researchers. We serve many B...
04/24/2024

Neuromics raison d'etre is providing human cells and related 3-D models to drug hunters and researchers. We serve many Bio-pharmas and academic/government labs. We proudly announce the addition of Insulin Secreting Human Fibroblast Pancreatic Islet Cells (https://www.neuromics.com/hpf002). We continue to add cells and models. Stay tuned. Diabetes Research Institute Foundation

Our Human Retinal Microvascular Endothelial Cells (HRMECs) (cat. HEC09) have a history of performing for researchers stu...
04/15/2024

Our Human Retinal Microvascular Endothelial Cells (HRMECs) (cat. HEC09) have a history of performing for researchers studying diabetic retinopathy. That continues, as another publication using them was released this month.

Learn more: https://www.neuromics.com/our-hrmecs-enable-diabetes-research

Eclipse day in Waco. Big thank you to Siri Lehmann, Sally Miller Walden, and Susan King. They allowed 80+ family and fri...
04/08/2024

Eclipse day in Waco. Big thank you to Siri Lehmann, Sally Miller Walden, and Susan King. They allowed 80+ family and friends to gather at Moon River Ranch. They arranged everything! Big thank you!!!

Planning any cell culturing projects this Spring? Now is the time to save big on our Preferred Fetal Bovine Serum (FBS)....
04/02/2024

Planning any cell culturing projects this Spring? Now is the time to save big on our Preferred Fetal Bovine Serum (FBS). Neuromics Preferred FBS is the best bang for your buck and is now only $250/500 ml through the end of May.

Learn more: https://www.neuromics.com/save-on-preferred-fbs-this-spring

Dr. Sonia Weimann and her team at Lehigh University published an important study on the mechanisms of hearing. The study...
04/01/2024

Dr. Sonia Weimann and her team at Lehigh University published an important study on the mechanisms of hearing. The study appeared in the "Journal of Neuroscience" (https://www.jneurosci.org/content/44/8/e0356232023.abstract). They made the cover, which features an image of our MAP-2 antibody. This study could build the foundation for future therapies. Society for Neuroscience Neuroscience News and Research Neuromics

The medial nucleus of the trapezoid body (MNTB) has been intensively investigated as a primary source of inhibition in brainstem auditory circuitry. MNTB-derived inhibition plays a critical role in the computation of sound location, as temporal features of sounds are precisely conveyed through the c...

Potent and effective! Check out this incredible media developed by Neuromics that stimulates neurite formation and promo...
03/25/2024

Potent and effective! Check out this incredible media developed by Neuromics that stimulates neurite formation and promotes the understanding of neurite outgrowth biology. Using this media, three-dimensional neurite tube structures can be formed in vitro in less than 18 hours. Neurons extend numerous processes that differentiate into dendrites and axons, essential for communication between neurons. This media can shed light on mechanisms underlying certain neurodegenerative diseases. Learn more about it here: https://www.neuromics.com/HNM004 Neuromics Neuroscience News and Research David Rupp

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5325 West 74th Street Suite 8
Edina, MN
55439

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Our unique value is based on providing reagents that are thoroughly tested and characterized. This includes tools and capabilities for cell based assays and gene expression analysis. We strive to find better ways to serve and provide value to our basic research and drug discovery customers.


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