Blue Dolphin Lead Discovery LLC

Blue Dolphin Lead Discovery LLC Blue Dolphin Lead Discovery is a fee-for-service, contract research organization focused on computer and structure-based ligand discovery.

Here is how we work with clients:

We do not retain any intellectual property
We begin with a preliminary consulation to understand the project - we will only undertake collaborations where we think we can contribute. For instance, in virtual screening applications we only begin the collaboration if the target is dockable. We perform an initial screen, and provide a preliminary report, including
r

aw screening output
hand-picked compounds we like, and other analysis
The client purchases and tests compounds
A final screen is performed based on the results of initial tests. Here is what we need to start a project:

A model of the target, preferably based on crystallography or NMR, though we have also worked with homology models. if possible, control information in the form of known actives and inactives
a robust assay (to be run by the client)
willingness to acquire and test compounds

Address

230 Hall Drive
Orinda, CA
94563

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