Her parents separated when she was six, and one of her biggest goals is to get them back together. Her best friend next to Shinichi is her classmate Sonoko. One year before the series' start, Ran and Shinichi had gone to the United States to visit Shinichi's parents in New York. They met his mother and her actress friend, Sharon Vineyard (also known as Vermouth, a member of the Black Organization)
. Later that evening, Vermouth disguised as a serial killer to do BO work, and was saved by Ran and Shinichi who encountered her on their way back from a show turned murder case. Vermouth had slipped and would have fallen to her death, but Ran caught her arm and Shinichi helped her pull her to safety. Due to this, Sharon gave Ran the nickname "Angel", and Shinichi the nickname "Cool Guy".[ Vermouth later showed hesitance to kill Ran and later Conan as well, but whether or not it was because of any emotional attachment is unclear. After Shinichi's disappearance, Ran met Conan Edogawa, who was introduced by Professor Agasa as a "distant relative" and asked Ran if she wouldn't mind taking care of him at her house. She and her father practically adopted him; Ran immediately came to think of him as a surrogate little brother.Little did (and still does) Ran know that "Conan" is actually Shinichi.